Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576561 | 0.90 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL10565850 | 0.87 | GPR84 (0.37) | LCKPPARDZDHHC20ZDHHC2FAAH | |
| SCHEMBL7634831 | 0.84 | ZDHHC7 (0.44) | FAAHASAH1ZDHHC7CNR1CNR2 | |
| SCHEMBL7643063 | 0.82 | TDP1 (0.41) | FAAHTRPA1ZDHHC7MAPT | |
| SCHEMBL27645892 | 0.82 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL7634025 | 0.81 | FAAH (0.41) | FAAHZDHHC7CNR1CNR2 | |
| SCHEMBL27861319 | 0.80 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL7931050 | 0.80 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL9697909 | 0.80 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL19745135 | 0.80 | LCK (0.41) | LCKPPARDZDHHC20ZDHHC2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096280-A | Arylenedioxy-bis-diketones | STERLING DRUG INC. (US) | 1978-06-20 | — | — | US | disclosed |