Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063818 | 0.89 | MTNR1A (0.45) | LMNAACHESMN1; SMN2KDM4EKMT2A | |
| SCHEMBL542640 | 0.83 | ACHE (0.58) | LMNAACHESMN1; SMN2TP53KMT2A | |
| SCHEMBL8894317 | 0.82 | LMNA (0.47) | LMNAACHESMN1; SMN2TP53KMT2A | |
| SCHEMBL316898 | 0.82 | MTNR1A (0.50) | LMNATP53KMT2AALDH1A1MEN1 | |
| SCHEMBL27591868 | 0.81 | HPGD (0.50) | LMNAKMT2AMEN1MAOB | |
| SCHEMBL4769156 | 0.81 | HSD17B10 (0.46) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL13763456 | 0.80 | LMNA (0.53) | LMNAPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL11682077 | 0.80 | SRC (0.49) | SMN1; SMN2KDM4EPOLBKMT2AALDH1A1 | |
| SCHEMBL24086431 | 0.80 | ACHE (0.59) | LMNAACHESMN1; SMN2TP53KMT2A | |
| SCHEMBL10063720 | 0.79 | POLB (0.46) | LMNAPOLBKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080454-A | 5-M-Tolyloxyuracil, anti-ulcer agent | PFIZER INC. (US) | 1978-03-21 | — | — | US | disclosed |