Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615455 | 1.00 | RAB9A (0.41) | RAB9AKDM4EPOLBPKMALDH1A1 | |
| SCHEMBL11617163 | 0.88 | KDM4E (0.39) | RAB9AKDM4EPOLBPKMALDH1A1 | |
| SCHEMBL11617162 | 0.88 | KDM4E (0.39) | RAB9AKDM4EPOLBPKMALDH1A1 | |
| SCHEMBL11618414 | 0.82 | KDM4E (0.36) | KDM4EPOLBPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL11618410 | 0.82 | KDM4E (0.36) | KDM4EPOLBPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL11614223 | 0.79 | KDM4E (0.47) | RAB9AKDM4EPOLBPKMALDH1A1 | |
| SCHEMBL11619320 | 0.77 | KDM4E (0.46) | RAB9AKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11619326 | 0.77 | KDM4E (0.46) | RAB9AKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11617675 | 0.75 | PKM (0.49) | KDM4EPOLBPKMALDH1A1 | |
| SCHEMBL11617679 | 0.75 | PKM (0.49) | KDM4EPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |