Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617679 | 1.00 | PKM (0.49) | PKMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL11617162 | 0.87 | KDM4E (0.39) | PKMKDM4EPOLBALDH1A1 | |
| SCHEMBL11617163 | 0.87 | KDM4E (0.39) | PKMKDM4EPOLBALDH1A1 | |
| SCHEMBL11613651 | 0.82 | KDM4E (0.46) | PKMKDM4EPOLBCCR2 | |
| SCHEMBL11618545 | 0.76 | KDM4E (0.61) | PKMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL11615455 | 0.75 | RAB9A (0.41) | PKMKDM4EPOLBALDH1A1 | |
| SCHEMBL11619447 | 0.74 | KDM4E (0.46) | PKMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL11617342 | 0.74 | POLB (0.44) | PKMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL11618414 | 0.72 | KDM4E (0.36) | PKMKDM4EPOLBALDH1A1 | |
| SCHEMBL11618410 | 0.72 | KDM4E (0.36) | PKMKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |