Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.35 |
| ▸ | LOX | P28300 | 3/20 | 0.35 |
| ▸ | AOC1 | P19801 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739697 | 0.82 | PRKCI (0.49) | PRKCIGRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL10883653 | 0.80 | JAK2 (0.41) | PRKCIGRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL21982078 | 0.78 | KDM4E (0.50) | PRKCILMNAKDM4ECYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL10883137 | 0.78 | GRIN2D (0.35) | PRKCIGRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL25099306 | 0.77 | HASPIN (0.43) | ADRA1AADRA1BLOXCYP1A2LMNA | |
| SCHEMBL11614989 | 0.77 | PRKCI (0.49) | PRKCIGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18880283 | 0.74 | PRMT6 (0.42) | LOXL2LOXLOXL3LMNAKDM4E | |
| SCHEMBL4265097 | 0.72 | — | — | |
| SCHEMBL1099009 | 0.72 | — | — | |
| SCHEMBL29654114 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |