Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457177 | 0.86 | ALDH1A1 (0.69) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27343663 | 0.86 | ALDH1A1 (0.69) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7145259 | 0.86 | ALDH1A1 (0.69) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL11027414 | 0.85 | ALDH1A1 (0.67) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27338710 | 0.85 | ALDH1A1 (0.67) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL8893513 | 0.85 | ALDH1A1 (0.67) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27338711 | 0.85 | ALDH1A1 (0.67) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9708620 | 0.85 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL24346312 | 0.83 | ALDH1A1 (0.72) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7139809 | 0.83 | OPRK1 (0.69) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116768-A | AMIDATION, METALLOPROTEINASE ENZYME | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1978-09-26 | — | — | US | disclosed |