SCHEMBL7139809

SCHEMBL7139809

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 1/20 0.69
▸ ALDH1A1 P00352 2/20 0.68
▸ THRB P10828 1/20 0.68
▸ CYP2C9 P11712 1/20 0.68
▸ CYP2C19 P33261 1/20 0.68
▸ HSD17B10 Q99714 1/20 0.68
▸ ATM Q13315 1/20 0.62
▸ POLB P06746 1/20 0.59
▸ LMNA P02545 1/20 0.56
▸ GLA P06280 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ CTSC P53634 1/20 0.56
▸ ANPEP P15144 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30581396 1.00 OPRK1 (0.69) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL28231245 1.00 OPRK1 (0.69) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL30581395 1.00 OPRK1 (0.69) OPRK1ALDH1A1THRBCYP2C9CYP2C19
Bromide SCHEMBL11571243 0.99 OPRK1 (0.67) OPRK1ALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL29661828 0.99 OPRK1 (0.67) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL20885112 0.97 OPRK1 (0.66) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL11597665 0.93 TSHR (0.67) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL10394119 0.93 TSHR (0.67) OPRK1ALDH1A1THRBCYP2C9CYP2C19
Trifluoroacetic Acid SCHEMBL11579813 0.93 OPRK1 (0.62) OPRK1ALDH1A1THRBCYP2C9CYP2C19
SCHEMBL11359300 0.93 TSHR (0.67) OPRK1ALDH1A1THRBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 — — US claimed
WO-2024261749-A1 ANTIMICROBIAL PEPTIDE-METAL COMPLEXES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-12-26 — — WO claimed
EP-4401555-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-07-24 — — EP claimed
US-20240206465-A1 ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-06-27 — — US claimed
EP-4326064-A1 ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2024-02-28 — — EP claimed
CN-116046861-A Manufacturing method of electrochemical sensor for promoting electron transfer 深圳可孚生物科技有限公司 2023-05-02 — — CN claimed
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 — — WO claimed
WO-2022224247-A1 ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-10-27 — — WO claimed
WO-2026099867-A1 SUSTAINABLE ANTIFREEZE COATINGS BY PEPTIDE SELF-ASSEMBLY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2026-05-15 — — WO disclosed
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2025-10-09 — — US disclosed
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 — — US disclosed
US-20250092088-A1 PEPTIDE COMPOUND PRODUCTION METHOD CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2025-03-20 — — US disclosed
WO-2024261749-A1 ANTIMICROBIAL PEPTIDE-METAL COMPLEXES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-12-26 — — WO disclosed
CN-113366011-B Process for producing peptide compound 日产化学株式会社 2024-08-16 — — CN disclosed
US-5214145-A Trisubstituted piperazin-2,5-diones EASTMAN KODAK COMPANY (US) 1993-05-25 — — US disclosed
US-5002872-A Peptides, Liquid Phase, Acetonitrile, Water W. R. GRACE & CO.-CONN. (US) 1991-03-26 — — US disclosed
US-4992552-A Process for preparation of amino acids EASTMAN KODAK COMPANY (US) 1991-02-12 — — US disclosed
EP-0272564-A2 Enzyme mediated coupling reactions HAMPSHIRE CHEMICAL CORPORATION (US) 1988-06-29 — — EP disclosed
US-4382889-A Epoxysuccinic acid derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 1983-05-10 — — US disclosed
US-4333879-A CALCIUM-ACTIVATED NEUTRAL THIOLPROTEASE INHIBITOR USED IN THE TREATMENT OF MUSCULAR DYSTROPHY TAISHO PHARMACEUTICAL CO., LTD. (JP) 1982-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240206465-A1 ACTIVE POLYMERIC FILMS AND POLYMERIC COMPOSITIONS PUF60, PARG, PGLS OPRK1 4359/4885ALDH1A1 4377/4885THRB 4617/4885
US-20250092088-A1 PEPTIDE COMPOUND PRODUCTION METHOD VIP, NPPA, HM13 OPRK1 4094/4885ALDH1A1 4107/4885THRB 1258/4885
US-20250313594-A1 TWO-RESIDUE-EXTENDED PEPTIDE AND METHOD FOR PRODUCING SAME NPPA, NGLY1, ANPEP OPRK1 3433/4885ALDH1A1 3754/4885THRB 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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