Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617148 | 0.72 | SMN1; SMN2 (0.42) | HPGDMEN1KMT2ATP53F2 | |
| SCHEMBL11616914 | 0.71 | TDP1 (0.44) | HPGDMEN1KMT2AALDH1A1APEX1 | |
| SCHEMBL11615066 | 0.70 | PKM (0.38) | MEN1KMT2APTGDR2ALDH1A1APEX1 | |
| SCHEMBL11508675 | 0.65 | CASR (0.36) | HTR6KMT2AF2 | |
| SCHEMBL11615840 | 0.65 | TDP1 (0.48) | HPGDMEN1KMT2AALDH1A1PTGS2 | |
| SCHEMBL11509774 | 0.64 | KCNN4 (0.38) | F2 | |
| SCHEMBL11615587 | 0.63 | TDP1 (0.49) | HPGDMEN1KMT2AMAOBF2 | |
| SCHEMBL13991168 | 0.61 | PTGS2 (0.42) | KMT2ATP53ALDH1A1PTGS2 | |
| SCHEMBL11616709 | 0.61 | NPC1 (0.50) | HPGDHTR6MEN1KMT2AF2 | |
| SCHEMBL11509098 | 0.61 | APEX1 (0.36) | HPGDMEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |