Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 7/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312954 | 0.81 | GSK3B (0.39) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL10416487 | 0.81 | GSK3B (0.39) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL4975646 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL2824441 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL10879454 | 0.77 | HPGD (0.36) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL3171915 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL3908443 | 0.75 | GSK3B (0.48) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL626418 | 0.74 | GSK3B (0.46) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL166123 | 0.74 | HPGD (0.47) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| Phthalimide SCHEMBL8455299 | 0.73 | GSK3B (0.47) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065212-A1 | NOVEL N3-AMINOALKYL DERIVATIVES OF 5-ARYLIDENEHYDANTOIN, PHARMACEUTICAL COMPOSITION CONTAINING THE ABOVE AND APPLICATION THEREOF | Uniwersytet Jagielloński (PL) | 2015-05-07 | — | — | WO | disclosed |
| US-4106940-A | N-ALKYLPHTHALIMIDE DERIVATIVE OIL FORMER | AGFA-GEVAERT, A.G. (DE) | 1978-08-15 | — | — | US | disclosed |