SCHEMBL3171915

SCHEMBL3171915

C=CC(c1ccccc1)c1cccc2c1C(=O)NC2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.40
▸ MAPT P10636 4/20 0.40
▸ CYP3A4 P08684 3/20 0.40
▸ ALOX15 P16050 3/20 0.40
▸ GSK3B P49841 1/20 0.40
▸ CASP3 P42574 6/20 0.40
▸ CASP2 P42575 2/20 0.40
▸ CASP7 P55210 2/20 0.40
▸ CASP6 P55212 2/20 0.40
▸ CASP8 Q14790 2/20 0.40
▸ HPGD P15428 4/20 0.39
▸ HSD17B10 Q99714 4/20 0.39
▸ LMNA P02545 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ TP53 P04637 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALOX12 P18054 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2312954 0.77 GSK3B (0.39) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL4975646 0.77 KDM4E (0.42) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL28247275 0.77 GSK3B (0.44) KDM4EGSK3BCASP3CASP2CASP7
SCHEMBL10416487 0.77 GSK3B (0.39) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL11615864 0.77 KDM4E (0.42) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL10879454 0.73 HPGD (0.36) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL3908443 0.72 GSK3B (0.48) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL166123 0.71 HPGD (0.47) KDM4EMAPTCYP3A4GSK3BCASP3
SCHEMBL29206318 0.71 KDM4E (0.41) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL9242437 0.70 KDM4E (0.47) KDM4EMAPTCYP3A4ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240288773-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE, AND COMPOSITION JSR CORPORATION (JP) 2024-08-29 — — US disclosed
WO-2023068075-A1 METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE AND RESIST UNDERLAYER FILM-FORMING COMPOSITION JSR株式会社 2023-04-27 — — WO disclosed
CN-106459259-B N-acetylglucosaminyl sugar chain group-containing compound, carrier compound for drug delivery, preparation, and drug delivery system 索马龙株式会社 2022-07-15 — — CN disclosed
EP-3147300-B1 N-ACETYLGLUCOSAMINE SUGAR CHAIN GROUP-CONTAINING POLYMER, CARRIER COMPOUND FOR DRUG DELIVERY, DRUG PREPARATION, AND DRUG DELIVERY SYSTEM SOMAR CORP (JP) 2020-06-24 — — EP disclosed
US-10471158-B2 N-acetylglucosamine sugar chain group-containing compound, carrier compound for drug delivery, drug preparation, and drug delivery system SOMAR CORPORATION (JP) 2019-11-12 — — US disclosed
US-20170095564-A1 N-ACETYLGLUCOSAMINE SUGAR CHAIN GROUP-CONTAINING COMPOUND, CARRIER COMPOUND FOR DRUG DELIVERY, DRUG PREPARATION, AND DRUG DELIVERY SYSTEM SOMAR CORPORATION (JP) 2017-04-06 — — US disclosed
EP-3147300-A1 N-ACETYLGLUCOSAMINE SUGAR CHAIN GROUP-CONTAINING COMPOUND, CARRIER COMPOUND FOR DRUG DELIVERY, DRUG PREPARATION, AND DRUG DELIVERY SYSTEM Somar Corporation (JP) 2017-03-29 — — EP disclosed
US-20100092445-A1 Adoptive immune cells for tumor vaccines SHUKOKAI INCORPORATED (JP) 2010-04-15 — — US disclosed
US-7655393-B2 Adoptive immune cells for tumor vaccines SHUKOKAI INCORPORATED (JP) 2010-02-02 — — US disclosed
EP-1757680-B1 Methods for cultivating antigen presenting cells SHUKOKAI INC (JP) 2009-09-16 — — EP disclosed
US-20090124706-A1 CONTACT LENS SOLUTION AND METHOD FOR HYDROPHILIZING CONTACT LENS BY USING THE SAME TOMEY CO., LTD (JP) 2009-05-14 — — US disclosed
EP-2042912-A1 LIQUID AGENT FOR CONTACT LENS AND METHOD FOR HYDROPHILIZING CONTACT LENS BY USING THE SAME Tomey Co., Ltd. (JP) 2009-04-01 — — EP disclosed
US-20070286847-A1 Adoptive Immune Cells For Tumor Vaccines SHUKOKAI INCORPORATED (JP) 2007-12-13 — — US disclosed
EP-1757680-A1 ADOPTIVE IMMUNOCYTE FOR TUMOR VACCINE AND THE LIKE Shukokai Incorporated (JP) 2007-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124706-A1 CONTACT LENS SOLUTION AND METHOD FOR HYDROPHILIZING CONTACT LENS BY USING THE SAME CRYZ, AQP1, CRYAB KDM4E 1663/4885MAPT 2374/4885CYP3A4 4165/4885
US-20170095564-A1 N-ACETYLGLUCOSAMINE SUGAR CHAIN GROUP-CONTAINING COMPOUND, CARRIER COMPOUND FOR DRUG DELIVERY, DRUG PREPARATION, AND DRUG DELIVERY SYSTEM VIM, SLC2A1, CD44 KDM4E 2948/4885MAPT 214/4885CYP3A4 4444/4885
US-20070286847-A1 Adoptive Immune Cells For Tumor Vaccines CD4, PBK, KIT KDM4E 1160/4885MAPT 1420/4885CYP3A4 3978/4885
US-20100092445-A1 Adoptive immune cells for tumor vaccines CD14, TSLP, CD4 KDM4E 2165/4885MAPT 887/4885CYP3A4 3920/4885
US-10471158-B2 N-acetylglucosamine sugar chain group-containing compound, carrier compound for drug delivery, drug preparation, and drug delivery system VIM, SLC2A1, CD44 KDM4E 2951/4885MAPT 216/4885CYP3A4 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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