Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 5/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312977 | 0.83 | KDM4E (0.42) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL10416487 | 0.83 | GSK3B (0.39) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL166123 | 0.82 | HPGD (0.47) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL2824441 | 0.79 | KDM4E (0.49) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL57295 | 0.79 | KDM4E (0.45) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL16754925 | 0.78 | GSK3B (0.62) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL1499914 | 0.77 | GSK3B (0.54) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL8356651 | 0.77 | KDM4E (0.43) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL4336651 | 0.77 | KDM4E (0.43) | GSK3BCASP3CASP7CASP2CASP6 | |
| SCHEMBL10925239 | 0.77 | ALDH1A1 (0.43) | GSK3BCASP3CASP7CASP2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431302-B1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO LTD (JP) | 2009-03-18 | — | — | EP | disclosed |
| CN-1747913-A | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | SEKISUI CHEMICAL CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| EP-1431302-A1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |