Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616273 | 0.78 | GID4 (0.41) | MAPTALDH1A1LMNACACNA1FTP53 | |
| SCHEMBL15715049 | 0.76 | MAPT (0.39) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL9833159 | 0.70 | ALDH1A1 (0.41) | TDP1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2973373 | 0.69 | SMN1; SMN2 (0.47) | TDP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL2346396 | 0.69 | KMT2A (0.46) | TDP1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL31728057 | 0.69 | IDO1 (0.51) | TDP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL11664605 | 0.69 | HSD17B10 (0.35) | MAPTALDH1A1GAACYP2C19HSD17B10 | |
| SCHEMBL10407685 | 0.69 | KMT2A (0.39) | TDP1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2828597 | 0.69 | IDO1 (0.51) | TDP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL11616842 | 0.68 | ALDH1A1 (0.43) | MAPTALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110465-A | ANTIINFLAMMATORY, ANTITHROMBOSIS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |