Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619505 | 0.91 | POLB (0.42) | MEN1KMT2AFAAHSMN1; SMN2NPSR1 | |
| SCHEMBL6608161 | 0.74 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2HTTPDE4A | |
| SCHEMBL11614116 | 0.73 | PTGIR (0.44) | SMN1; SMN2LMNAKDM4EPTGIR | |
| SCHEMBL11471800 | 0.70 | CYP1A2 (0.40) | MEN1KMT2AFAAHSMN1; SMN2NPSR1 | |
| SCHEMBL11611698 | 0.70 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL8890615 | 0.65 | HTT (0.51) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL11614807 | 0.63 | PTGDR2 (0.42) | MEN1KMT2ANPSR1HTTDHODH | |
| SCHEMBL11615729 | 0.63 | TP53 (0.45) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL11616871 | 0.63 | GAA (0.44) | MEN1KMT2AFAAHSMN1; SMN2HTT | |
| SCHEMBL3494751 | 0.63 | ALDH1A1 (0.52) | MEN1KMT2ASMN1; SMN2NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |