Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140272 | 0.84 | MEN1 (0.48) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15946997 | 0.82 | PTGER4 (0.66) | HTTMEN1KMT2APTGER4AKR1C3 | |
| SCHEMBL8887875 | 0.81 | MEN1 (0.51) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8889942 | 0.81 | HTT (0.48) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8887318 | 0.80 | KMT2A (0.52) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8886445 | 0.79 | MEN1 (0.48) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10140278 | 0.78 | SMN1; SMN2 (0.48) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3494751 | 0.78 | ALDH1A1 (0.52) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL6258294 | 0.77 | EDNRB (0.53) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3492508 | 0.76 | F2RL3 (0.61) | MEN1KMT2ASMN1; SMN2NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |