SCHEMBL466590

SCHEMBL466590

CC(c1ccccc1)c1cc(C(C)c2ccccc2)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.47
RAB9A P51151 6/20 0.47
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
NPSR1 Q6W5P4 2/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
KDM4E B2RXH2 4/20 0.36
HPGD P15428 3/20 0.36
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9183011 0.89 NPC1 (0.58) NPC1RAB9ALMNAPOLBTYR
SCHEMBL11620211 0.88 NPC1 (0.45) NPC1RAB9ALMNAPOLBTYR
SCHEMBL11615531 0.88 NPC1 (0.50) NPC1RAB9ALMNAPOLBTYR
SCHEMBL947944 0.86 NPC1 (0.45) NPC1RAB9ALMNAPOLBTYR
SCHEMBL301989 0.85 NPC1 (0.47) NPC1RAB9ALMNAPOLBTYR
SCHEMBL9468024 0.84 NPC1 (0.41) NPC1RAB9ALMNAPOLBTYR
SCHEMBL11621092 0.81 NPC1 (0.59) NPC1RAB9ALMNAPOLBTYR
SCHEMBL30290848 0.81 NPC1 (0.40) NPC1RAB9ALMNAPOLBTYR
SCHEMBL11616637 0.81 NPC1 (0.43) NPC1RAB9ALMNAPOLBTYR
SCHEMBL4357048 0.81 NPC1 (0.50) NPC1RAB9ALMNAPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119177078-A Antistatic composition and antistatic polyester film using the same 东丽先端素材株式会社 2024-12-24 CN claimed
US-20260098129-A1 THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-04-09 US disclosed
US-20260071030-A1 THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-12 US disclosed
US-20260062520-A1 THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-05 US disclosed
EP-4631994-A1 THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-15 EP disclosed
EP-4631995-A1 THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-15 EP disclosed
EP-4631991-A1 THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-15 EP disclosed
EP-3957683-B1 LUMINOUS POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI ENG PLASTICS CORP (JP) 2025-10-08 EP disclosed
US-12325796-B2 Methods for producing polycarbonate copolymer and polysiloxane compound, polycarbonate copolymer, polysiloxane compound, composition, and molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-06-10 US disclosed
US-12304998-B2 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-20 US disclosed
US-20110269882-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION, METHOD FOR PRODUCING THE RESIN COMPOSITION, AND MOLDED ARTICLE OF THE SAME MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-11-03 US disclosed
US-20110100861-A1 PLASTIC AMPULE AND COLORED PLASTIC CONTAINER OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2011-05-05 US disclosed
EP-2266521-A1 PLASTIC AMPULE AND COLORED PLASTIC CONTAINER Otsuka Pharmaceutical Factory, Inc. (JP) 2010-12-29 EP disclosed
EP-1217040-B1 Polycarbonate resin composition and its molded articles MITSUBISHI ENG PLASTICS CORP (JP) 2005-03-02 EP disclosed
US-6664313-B2 Heat stability, light reflectance, flame retardancy MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2003-12-16 US disclosed
US-20020146550-A1 Polycarbonate resin composition and its molded articles MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-10-10 US disclosed
EP-1217040-A1 Polycarbonate resin composition and its molded articles MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-06-26 EP disclosed
US-5264406-A Alkali or alkaline metal hypophosphites with amines INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-23 US disclosed
US-5264541-A Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-23 US disclosed
US-5260246-A Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062520-A1 THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN RER1, PUF60, SEM1 NPC1 3995/4885RAB9A 1655/4885LMNA 3466/4885
US-20260071030-A1 THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS DERL1, WDR1, RIF1 NPC1 3475/4885RAB9A 2718/4885LMNA 2015/4885
US-20260098129-A1 THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN RER1, EIF2AK1, RIOK1 NPC1 3538/4885RAB9A 1860/4885LMNA 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.