Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617140 | 0.94 | KMT2A (0.49) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11616199 | 0.90 | ALDH1A1 (0.54) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11619781 | 0.89 | ALDH1A1 (0.53) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11615957 | 0.88 | POLB (0.50) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11618944 | 0.88 | ALDH1A1 (0.54) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11375069 | 0.84 | KMT2A (0.52) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11616203 | 0.84 | ALDH1A1 (0.51) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL20827130 | 0.83 | GPR35 (0.60) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL8780440 | 0.83 | ALDH1A1 (0.50) | KMT2AKDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL11616923 | 0.82 | HPGD (0.51) | KMT2AKDM4EPOLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107310-A | ANALGESICS | ROUSSEL UCLAF (FR) | 1978-08-15 | — | — | US | disclosed |