Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616203 | 0.94 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11619781 | 0.94 | ALDH1A1 (0.53) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11617140 | 0.90 | KMT2A (0.49) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8780424 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11616199 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11616923 | 0.85 | HPGD (0.51) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8780472 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11617138 | 0.83 | KMT2A (0.52) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11615957 | 0.81 | POLB (0.50) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11619662 | 0.81 | POLB (0.51) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498722-B1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1997-07-30 | — | — | EP | claimed |
| US-4107310-A | ANALGESICS | ROUSSEL UCLAF (FR) | 1978-08-15 | — | — | US | disclosed |