Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.86 |
| ▸ | NT5E | P21589 | 1/20 | 0.86 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NAMPT | P43490 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | TYK2 | P29597 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242053 | 0.90 | GAA (1.00) | MAPK1KMT2ANT5EGAAKDM4E | |
| SCHEMBL10939703 | 0.86 | NPC1 (0.76) | MAPK1KMT2ANT5EMEN1LMNA | |
| SCHEMBL1898755 | 0.86 | GAA (0.91) | MAPK1KMT2ANT5EGAAKDM4E | |
| SCHEMBL9767723 | 0.86 | NPC1 (0.76) | MAPK1KMT2ANT5EMEN1LMNA | |
| SCHEMBL611657 | 0.86 | NPC1 (0.76) | MAPK1KMT2ANT5EMEN1LMNA | |
| SCHEMBL5223022 | 0.85 | POLB (0.75) | MAPK1KMT2ANT5EGAAHTT | |
| SCHEMBL19241697 | 0.85 | GAA (0.88) | MAPK1KMT2ANT5EGAAKDM4E | |
| SCHEMBL7461375 | 0.84 | GAA (0.79) | MAPK1KMT2ANT5EGAAKDM4E | |
| SCHEMBL10016472 | 0.83 | RAB9A (0.77) | MAPK1KMT2ANT5EGAAKDM4E | |
| SCHEMBL23734986 | 0.83 | GAA (0.85) | MAPK1KMT2ANT5EGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-4008326-A | INCREASING PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |