Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | NT5E | P21589 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.68 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.68 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611657 | 1.00 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL10939703 | 1.00 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL674167 | 0.92 | HDAC8 (0.69) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL27918627 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL6556039 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL2409003 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL6710662 | 0.92 | MITF (0.68) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL493839 | 0.90 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL3823913 | 0.90 | PTPN1 (0.73) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL21698103 | 0.90 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2KMT2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066776-A | From dihaloaromatic compound, in situ generation of alkali sulfides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-19 | — | — | US | disclosed |