Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | NT5E | P21589 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.68 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.68 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939703 | 1.00 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL9767723 | 1.00 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL674167 | 0.92 | HDAC8 (0.69) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL27918627 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL6556039 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL2409003 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL6710662 | 0.92 | MITF (0.68) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL493839 | 0.90 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL3823913 | 0.90 | PTPN1 (0.73) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL21698103 | 0.90 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2KMT2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420484-B | Method for preparing amide compounds | 四川大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118420484-A | Method for preparing amide compounds | 四川大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| US-20220162224-A1 | P38ALPHA MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS | GEN1E LIFESCIENCES INC. | 2022-05-26 | — | — | US | disclosed |
| EP-2206547-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND PROCESSES FOR THE PRODUCTION OF THE SAME, POLYMERS AND PROTON CONDUCTIVE MEMBRANES OF THESE COMPOUNDS | JSR CORP (JP) | 2016-03-16 | — | — | EP | disclosed |
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738194-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND APPLICATION THEREOF | JSR Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| EP-1906473-B1 | ELECTRODE PASTE FOR USE IN SOLID POLYMER FUEL CELL | JSR CORP (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8399148-B2 | Varnish for a solid polymer fuel cell | JSR CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| EP-1947717-B1 | ELECTRODE CATALYST LAYER | JSR CORP (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-20030173547-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1329444-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR Corporation (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-20020177656-A1 | Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same | JSR CORPORATION (JP) | 2002-11-28 | — | — | US | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-1245554-A1 | Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same | JSR Corporation (JP) | 2002-10-02 | — | — | EP | disclosed |
| WO-1996010560-A1 | BENZAMIDE SEMICARBAZONE DERIVATIVES AND THEIR USE AS PESTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| US-4499167-A | Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0051828-B1 | N-BENZOYL-ALPHA-ANILINO ALKANE CARBOXYLIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4386031-A | ANTICOAGULANTS; ANTIALLERGENS; ANTINFLAM-MATORY AND ANTILIPEMIC AGENTS; ANTIHISTAMINES; CARDIOVASCULAR DISORDERS | A. NATTERMANN & CIE GMBH (DE) | 1983-05-31 | — | — | US | disclosed |
| EP-0051828-A1 | N-benzoyl-alpha-anilino alkane carboxylic acids, salts and esters thereof, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162224-A1 | P38ALPHA MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS | MAPKAPK2, MAPK1, MAPK8 | NPC1 2511/4885RAB9A 2172/4885SMN1; SMN2 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.