Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624836 | 0.77 | SLC2A1 (0.44) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| Hydrochloric Acid SCHEMBL11621332 | 0.76 | SLC2A1 (0.46) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| SCHEMBL11620162 | 0.74 | MEN1 (0.44) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| SCHEMBL6629100 | 0.70 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| Hydrochloric Acid SCHEMBL11286678 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| SCHEMBL23073294 | 0.66 | ABCB11 (0.47) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL11623005 | 0.65 | SLC2A1 (0.44) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| SCHEMBL23073289 | 0.65 | KDM1A (0.35) | KDM4EALDH1A1MEN1KMT2APABPC1 | |
| SCHEMBL2579002 | 0.64 | HRH3 (0.66) | — | |
| Hydrochloric Acid SCHEMBL28918885 | 0.63 | NPBWR1 (0.55) | KDM4EALDH1A1MEN1KMT2APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |