Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358475 | 0.88 | KDM4E (0.53) | POLBTDP1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL11621722 | 0.83 | AKR1C3 (0.47) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL11619384 | 0.81 | KDM4E (0.54) | POLBTDP1L3MBTL1KDM4EELANE | |
| SCHEMBL1558507 | 0.79 | L3MBTL1 (0.51) | L3MBTL1KDM4ECYP1A2CYP2D6HPGD | |
| SCHEMBL19320835 | 0.78 | ACMSD (0.53) | CYP2C19 | |
| SCHEMBL11617866 | 0.78 | HSD17B3 (0.47) | POLBTDP1L3MBTL1CYP1A2HPGD | |
| SCHEMBL534811 | 0.77 | HTT (0.56) | TDP1KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL31617745 | 0.77 | HTT (0.56) | TDP1KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL8082162 | 0.76 | HPGD (0.71) | L3MBTL1KDM4ECYP1A2CYP2D6HPGD | |
| SCHEMBL27541096 | 0.76 | LMNA (0.50) | POLBTDP1L3MBTL1KDM4ECDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127666-A | ANTIEMETIC | UNIVERSITE D'ORLEANS (FR) | 1978-11-28 | — | — | US | disclosed |