Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616625 | 0.90 | PTGDR2 (0.41) | PTGDR2PPARGPPARDPPARARXRA | |
| SCHEMBL11636674 | 0.84 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL11615839 | 0.80 | PTGDR2 (0.47) | PTGDR2NPSR1 | |
| SCHEMBL11511280 | 0.74 | PDE2A (0.39) | — | |
| SCHEMBL11617121 | 0.73 | PTGDR2 (0.40) | PTGDR2 | |
| SCHEMBL11611744 | 0.70 | GRN (0.43) | — | |
| SCHEMBL28785118 | 0.69 | ALDH1A1 (0.41) | L3MBTL1 | |
| SCHEMBL11618315 | 0.68 | PTGDR2 (0.48) | PTGDR2NPSR1 | |
| SCHEMBL11619505 | 0.67 | POLB (0.42) | PTGDR2NPSR1 | |
| SCHEMBL11619251 | 0.67 | SLC22A12 (0.51) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |