Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701061 | 0.77 | SLC6A4 (0.41) | SLC6A4SLC6A3 | |
| SCHEMBL15484875 | 0.77 | — | — | |
| SCHEMBL2943296 | 0.77 | GRM5 (0.37) | SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9322185 | 0.73 | TSHR (0.37) | MAPTHPGDSMN1; SMN2HSD17B10KCNH2 | |
| SCHEMBL3058072 | 0.73 | SLC22A12 (0.48) | SMN1; SMN2 | |
| SCHEMBL17041433 | 0.73 | MAOA (0.34) | MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL11619962 | 0.73 | SLC6A4 (0.45) | HPGDSLC6A2SLC6A4SLC6A3GRIN1 | |
| SCHEMBL11066307 | 0.71 | SIGMAR1 (0.50) | MAPTHSD17B10GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL29159181 | 0.70 | MAPT (0.32) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL104561 | 0.68 | ALDH1A1 (0.40) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111873-A | DITHIO COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1978-09-05 | — | — | US | disclosed |