SCHEMBL11618969

SCHEMBL11618969

CCOc1nn(-c2ccccc2Cl)c(=O)o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.55
BCHE P06276 1/20 0.52
LIPC P11150 1/20 0.52
ACHE P22303 1/20 0.52
LIPE Q05469 1/20 0.52
PDE4B Q07343 3/20 0.45
MAPK14 Q16539 1/20 0.41
PDE4A P27815 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
CNR1 P21554 2/20 0.40
ELANE P08246 1/20 0.40
FAAH O00519 1/20 0.39
SLC16A3 O15427 1/20 0.39
SLC16A1 P53985 1/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11619856 0.86 MGLL (0.50) MGLLBCHELIPCACHELIPE
SCHEMBL11556228 0.84 MGLL (0.56) MGLLBCHELIPCACHELIPE
SCHEMBL11618467 0.84 FAAH (0.55) MGLLMAPK14FAAH
SCHEMBL11620114 0.84 MGLL (0.50) MGLLBCHELIPCACHELIPE
SCHEMBL11622573 0.84 MGLL (0.50) MGLLBCHELIPCACHELIPE
SCHEMBL11621692 0.83 MGLL (0.55) MGLLBCHELIPCACHELIPE
SCHEMBL2235276 0.82 MGLL (0.54) MGLLBCHELIPCACHELIPE
SCHEMBL11618056 0.81 MGLL (0.50) MGLLBCHELIPCACHELIPE
SCHEMBL2233786 0.80 MGLL (0.76) MGLLBCHELIPCACHELIPE
SCHEMBL9553657 0.77 MGLL (0.47) MGLLCNR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US claimed
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US disclosed