SCHEMBL11618467

SCHEMBL11618467

COc1nn(-c2ccccc2Cl)c(=O)o1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 10/20 0.55
MGLL Q99685 7/20 0.55
ABHD16A O95870 2/20 0.52
MAPK11 Q15759 1/20 0.45
MAPK14 Q16539 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11620913 0.88 MGLL (0.50) FAAHMGLLABHD16A
SCHEMBL11618969 0.84 MGLL (0.55) FAAHMGLLMAPK14
SCHEMBL74675 0.83 ABHD16A (0.57) FAAHMGLLABHD16A
SCHEMBL11620519 0.82 FAAH (0.55) FAAHMGLLABHD16A
SCHEMBL11623485 0.82 FAAH (0.55) FAAHMGLLABHD16A
SCHEMBL2237059 0.82 ABHD16A (0.60) FAAHMGLLABHD16A
SCHEMBL11621778 0.81 ABHD16A (0.52) FAAHMGLLABHD16A
SCHEMBL9553657 0.80 MGLL (0.47) FAAHMGLL
SCHEMBL7044246 0.80 ABHD16A (0.48) FAAHMGLLABHD16A
SCHEMBL11558856 0.79 FAAH (0.52) FAAHMGLLABHD16A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US claimed
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US disclosed