Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617359 | 0.88 | CYP2D6 (0.35) | PRKCIHTTTSHRADRB2CYP2D6 | |
| SCHEMBL11620212 | 0.86 | ADRB2 (0.38) | ACHEHTTALDH1A1KDM4EMEN1 | |
| SCHEMBL11623888 | 0.84 | SLC6A2 (0.38) | HTTALDH1A1KDM4EMEN1POLB | |
| SCHEMBL11619496 | 0.79 | CYP2D6 (0.50) | HTTALDH1A1KDM4ETSHRADRB2 | |
| SCHEMBL11621366 | 0.76 | PRKCI (0.43) | PRKCIACHEHTTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11622600 | 0.74 | ACHE (0.45) | PRKCIACHEHTTALDH1A1KDM4E | |
| SCHEMBL11622053 | 0.74 | HTT (0.44) | PRKCIACHEHTTALDH1A1KDM4E | |
| SCHEMBL11251739 | 0.74 | ALDH1A1 (0.40) | PRKCIACHEHTTALDH1A1KDM4E | |
| SCHEMBL11621102 | 0.73 | PRKCI (0.41) | PRKCIACHEHTTALDH1A1KDM4E | |
| SCHEMBL11615617 | 0.73 | POLB (0.54) | PRKCIACHEHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |