Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618844 | 0.81 | ALDH1A1 (0.61) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL4188069 | 0.78 | DDAH1 (0.59) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL69998 | 0.76 | RAB9A (0.56) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL3176468 | 0.76 | KMT2A (0.59) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL11561776 | 0.74 | RAB9A (0.57) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL9305001 | 0.73 | KMT2A (0.56) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL3500434 | 0.72 | RAB9A (0.76) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL18758063 | 0.72 | DDAH1 (0.57) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL18776132 | 0.72 | DDAH1 (0.53) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL2488619 | 0.71 | RAB9A (0.65) | RAB9AKMT2AMEN1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119780-A | 2(Isopropyldithio)benzimidazole | MONSANTO COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4006155-A | Method for preparation of phosphorus polysulfides | MONSANTO COMPANY (US) | 1977-02-01 | — | — | US | disclosed |