Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 7/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286641 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL12971 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9209215 | 0.80 | KDM4E (0.69) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL15078645 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11873113 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11337791 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL175163 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL12377803 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL17922270 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL13680663 | 0.73 | KDR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104053-A | 3-Benzyl-2-methylimino-5-phenyl-Δ4 -1,3,4-thiadiazolines and method of combating undesired plant growth | GULF OIL CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |