Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 5/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619783 | 0.81 | ALDH1A1 (0.65) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29367007 | 0.80 | NPC1 (0.58) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28593204 | 0.80 | NPC1 (0.58) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9209215 | 0.78 | KDM4E (0.69) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL175032 | 0.77 | KDM4E (0.53) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27183245 | 0.76 | KMT2A (0.54) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL603197 | 0.76 | KDM4E (0.65) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8042130 | 0.76 | HSD17B1 (0.46) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL22725686 | 0.75 | AAK1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL11399969 | 0.75 | HDAC1 (0.57) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032193-A1 | SUBSTITUTED THIADIAZOLINES USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-30 | — | — | WO | disclosed |
| US-4112230-A | Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4104053-A | 3-Benzyl-2-methylimino-5-phenyl-Δ4 -1,3,4-thiadiazolines and method of combating undesired plant growth | GULF OIL CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4020078-A | HERBICIDES | GULF OIL CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |