Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826025 | 0.73 | LMNA (0.55) | NR1H3ESR1ESR2POLBCYP3A4 | |
| SCHEMBL20243060 | 0.73 | HTT (0.40) | CASP1NR1H3GRM1GRM4HTT | |
| SCHEMBL5903053 | 0.73 | NPC1 (0.51) | GRM1GRM4ESR1ESR2POLB | |
| SCHEMBL11620020 | 0.72 | CYP3A4 (0.49) | CASP1NR1H3GRM1GRM4POLB | |
| SCHEMBL19766161 | 0.72 | GRM1 (0.45) | CASP1NR1H3GRM1GRM4HTT | |
| SCHEMBL30946497 | 0.70 | HCAR1 (0.37) | CYP1A2MAPK1CYP3A4PMP22HCAR1 | |
| SCHEMBL15272283 | 0.70 | NR1H3 (0.45) | NR1H3ESR1ESR2POLBCYP3A4 | |
| SCHEMBL17028327 | 0.69 | NR1H3 (0.44) | CASP1NR1H3HTTSCN2AMEN1 | |
| SCHEMBL24425914 | 0.69 | MEN1 (0.53) | NR1H3ESR1ESR2SCN2AMEN1 | |
| SCHEMBL29906067 | 0.69 | MEN1 (0.53) | NR1H3ESR1ESR2SCN2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124375-A | Substituted phthalimides for regulating the growth of plants | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| US-4124375-A | Substituted phthalimides for regulating the growth of plants | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |