Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30946425 | 0.79 | NT5E (0.35) | HCAR1KDM1ACYP11B1CYP11B2NT5E | |
| SCHEMBL14320657 | 0.79 | GAA (0.50) | NTRK1MEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL30946430 | 0.79 | GAA (0.50) | NTRK1MEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL31284223 | 0.73 | HCAR1 (0.32) | HCAR1KDM1A | |
| SCHEMBL31284605 | 0.72 | ABCC8 (0.41) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL12099741 | 0.72 | MAPK1 (0.38) | KDM1AMAPTMAPK1 | |
| SCHEMBL12684833 | 0.71 | NOTUM (0.51) | KDM1AALDH1A1MAPTNOTUMXPO1 | |
| SCHEMBL11619972 | 0.70 | CASP1 (0.44) | HCAR1MEN1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL6267032 | 0.69 | KDM1A (0.50) | HCAR1KDM1ACYP11B1CYP11B2NOTUM | |
| SCHEMBL30864218 | 0.69 | KDM1A (0.50) | HCAR1KDM1ACYP11B1CYP11B2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634161-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024130166-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-06-20 | — | — | WO | disclosed |