Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622966 | 0.93 | MEN1 (0.45) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11619369 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11624689 | 0.85 | ALDH1A1 (0.48) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11622323 | 0.83 | LMNA (0.39) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11621422 | 0.82 | CSNK1D (0.41) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11622312 | 0.81 | AURKA (0.44) | POLBALDH1A1GAAKDM4ETP53 | |
| SCHEMBL11623223 | 0.80 | KMT2A (0.41) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11623222 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL11620512 | 0.77 | POLB (0.40) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11622045 | 0.77 | LMNA (0.44) | MEN1KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |