Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622323 | 0.85 | LMNA (0.39) | ALDH1A1LRRK2LMNAKDM4EGAA | |
| SCHEMBL11621422 | 0.84 | CSNK1D (0.41) | ALDH1A1LMNAKDM4EGAAKMT2A | |
| SCHEMBL11622312 | 0.83 | AURKA (0.44) | ALDH1A1LMNAKDM4EGAAPOLB | |
| SCHEMBL11623223 | 0.82 | KMT2A (0.41) | ALDH1A1LMNAKDM4EGAAKMT2A | |
| SCHEMBL11619369 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LRRK2LMNAGAAKMT2A | |
| SCHEMBL11624689 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL11620936 | 0.80 | MEN1 (0.43) | ALDH1A1LMNAKDM4EGAAKMT2A | |
| SCHEMBL11620512 | 0.79 | POLB (0.40) | ALDH1A1LRRK2LMNAKDM4EGAA | |
| SCHEMBL11622966 | 0.78 | MEN1 (0.45) | ALDH1A1KDM4EGAAKMT2APOLB | |
| SCHEMBL11620869 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |