Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 11/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 3/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258832 | 0.82 | PI4KB (0.59) | ALDH1A1PDE2API4KBNPC1RAB9A | |
| SCHEMBL11151131 | 0.82 | PDE2A (0.45) | ALDH1A1MAPTALOX15NPSR1PDE2A | |
| SCHEMBL11733042 | 0.82 | PDE2A (0.45) | ALDH1A1MAPTALOX15NPSR1PDE2A | |
| SCHEMBL11257304 | 0.81 | PDE2A (0.44) | ALDH1A1MAPTALOX15NPSR1PDE2A | |
| SCHEMBL11621025 | 0.80 | PDE2A (0.48) | ALDH1A1MAPTALOX15NPSR1PDE2A | |
| SCHEMBL11167751 | 0.79 | NOD1 (0.59) | NOD1CXCL8ALDH1A1NOD2GAA | |
| SCHEMBL11167754 | 0.79 | NOD1 (0.59) | NOD1CXCL8ALDH1A1NOD2GAA | |
| SCHEMBL11148706 | 0.76 | NOD1 (0.57) | NOD1CXCL8ALDH1A1MAPTNOD2 | |
| SCHEMBL11148703 | 0.76 | NOD1 (0.57) | NOD1CXCL8ALDH1A1MAPTNOD2 | |
| SCHEMBL11156270 | 0.76 | NOD1 (0.57) | NOD1CXCL8ALDH1A1NOD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | claimed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |