Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619959 | 0.81 | TNKS2 (0.37) | ALDH1A1HSD17B10KDM4ECYP1A2CYP2C19 | |
| SCHEMBL11549367 | 0.77 | TOP2A (0.50) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4936991 | 0.76 | TOP2A (0.58) | ALDH1A1KDM4EMAPTTOP2ATOP2B | |
| SCHEMBL29965486 | 0.76 | TOP2A (0.58) | ALDH1A1KDM4EMAPTTOP2ATOP2B | |
| SCHEMBL11546703 | 0.72 | TNKS2 (0.46) | ALDH1A1KDM4ETDP1MAPTTOP2A | |
| SCHEMBL11667578 | 0.69 | HCAR2 (0.56) | KDM4EPARP1LMNAMEN1KMT2A | |
| SCHEMBL160155 | 0.68 | AURKA (0.61) | ALDH1A1HSD17B10KDM4ERAB9AMAPT | |
| SCHEMBL29414293 | 0.68 | AURKA (0.61) | ALDH1A1HSD17B10KDM4ERAB9AMAPT | |
| SCHEMBL4097753 | 0.68 | KDM4E (0.43) | ALDH1A1HSD17B10KDM4ECYP1A2CYP2C19 | |
| SCHEMBL11548593 | 0.68 | KDM4E (0.59) | ALDH1A1HSD17B10KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | claimed |
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | disclosed |
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | disclosed |
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | disclosed |