Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 4/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.58 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.58 |
| ▸ | TNKS | O95271 | 2/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936991 | 1.00 | TOP2A (0.58) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL28060714 | 0.86 | BRD4 (0.59) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL941961 | 0.86 | QTRT1 (0.59) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL27334538 | 0.84 | BRD4 (0.74) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL8187460 | 0.84 | TOP2A (0.59) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL11548593 | 0.83 | KDM4E (0.59) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL28851317 | 0.82 | TOP2A (0.44) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL942595 | 0.82 | MAPT (0.56) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL6157123 | 0.82 | MAPT (0.56) | TOP2ATOP2BBRD4PARP1TNKS2 | |
| SCHEMBL11499700 | 0.82 | TOP2A (0.52) | TOP2ATOP2BBRD4PARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109050-A | Preparation method and application of quinazolinone-based 1,3, 4-oxadiazole compound | 天津理工大学 | 2022-09-27 | — | — | CN | claimed |
| CN-117384156-B | Preparation method and application of camelning alkali A and derivative thereof | 烟台大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-117384156-A | Preparation method and application of camelning alkali A and derivative thereof | 烟台大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115109050-A | Preparation method and application of quinazolinone-based 1,3, 4-oxadiazole compound | 天津理工大学 | 2022-09-27 | — | — | CN | disclosed |