Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550579 | 0.80 | PDE3B (0.42) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29965486 | 0.74 | TOP2A (0.58) | TNKS2MAPTTOP2ATOP2BBRD4 | |
| SCHEMBL4936991 | 0.74 | TOP2A (0.58) | TNKS2MAPTTOP2ATOP2BBRD4 | |
| SCHEMBL11622307 | 0.72 | ALDH1A1 (0.46) | TNKS2MAPTTOP2ATOP2BBRD4 | |
| SCHEMBL11549078 | 0.72 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11549367 | 0.71 | TOP2A (0.50) | TNKS2MAPTTOP2ATOP2BBRD4 | |
| SCHEMBL8189628 | 0.71 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11667578 | 0.70 | HCAR2 (0.56) | PARP1MEN1KMT2AKDM4E | |
| SCHEMBL11619959 | 0.69 | TNKS2 (0.37) | TNKS2BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL2534987 | 0.69 | PDE10A (0.49) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |