Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066960 | 0.77 | GAA (0.48) | ALDH1A1GAAKMT2ARAB9ANPC1 | |
| SCHEMBL22992354 | 0.76 | CYP1A2 (0.42) | ALDH1A1KMT2AOPRM1CYP1A2CYP2D6 | |
| SCHEMBL30799429 | 0.74 | PIN1 (0.64) | ALDH1A1GAAKMT2ARAB9ANPC1 | |
| SCHEMBL7817290 | 0.72 | EDNRA (0.61) | ALDH1A1KMT2ACES2CES1SMN1; SMN2 | |
| SCHEMBL7945706 | 0.72 | ALDH1A1 (0.54) | ALDH1A1GAAKMT2ARAB9ANPC1 | |
| SCHEMBL8048881 | 0.72 | MEN1 (0.44) | ALDH1A1GAAKMT2AOPRM1CYP1A2 | |
| SCHEMBL8047735 | 0.72 | MEN1 (0.44) | ALDH1A1GAAKMT2AOPRM1CYP1A2 | |
| SCHEMBL27456073 | 0.71 | EDNRA (0.52) | ALDH1A1GAARAB9ANPC1CYP1A2 | |
| SCHEMBL6995755 | 0.71 | ALDH1A1 (0.65) | ALDH1A1GAAKMT2ARAB9ANPC1 | |
| SCHEMBL28127659 | 0.71 | ALDH1A1 (0.41) | ALDH1A1GAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075223-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4017546-A | AROYL PHENYL INDENES AND AROYL PHENYL NAPHTHALENES | ELI LILLY AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |