Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936317 | 0.86 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2SIGMAR1CYP1A2 | |
| SCHEMBL246639 | 0.84 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2SIGMAR1CYP1A2 | |
| SCHEMBL28539349 | 0.82 | CHRM2 (0.50) | MEN1KMT2ASMN1; SMN2SIGMAR1CYP1A2 | |
| SCHEMBL10598204 | 0.79 | ESR1 (0.57) | KIF11MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL11623208 | 0.79 | CYP2C9 (0.48) | KIF11MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL12441784 | 0.79 | MEN1 (0.57) | KIF11MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL11764401 | 0.79 | SMN1; SMN2 (0.44) | KIF11MEN1KMT2ASMN1; SMN2SIGMAR1 | |
| SCHEMBL11623432 | 0.77 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2SIGMAR1CYP1A2 | |
| SCHEMBL11625992 | 0.77 | BCL2 (0.58) | KIF11MEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL1129210 | 0.77 | SMN1; SMN2 (0.43) | KIF11MEN1KMT2ASMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094908-A | Alpha-substituted benzhydrol derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-06-13 | — | — | US | disclosed |
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |