SCHEMBL246639

SCHEMBL246639

CCC(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
SIGMAR1 Q99720 1/20 0.50
CHRM2 P08172 4/20 0.47
CHRM4 P08173 4/20 0.47
CHRM5 P08912 4/20 0.47
CHRM1 P11229 4/20 0.47
CHRM3 P20309 4/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP1A2 P05177 2/20 0.44
KCNN4 O15554 1/20 0.44
CYP2D6 P10635 2/20 0.44
CYP3A4 P08684 1/20 0.42
HIF1A Q16665 1/20 0.42
LMNA P02545 1/20 0.42
HTR1A P08908 1/20 0.42
OPRM1 P35372 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL936317 0.97 SMN1; SMN2 (0.50) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL28539349 0.97 CHRM2 (0.50) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL11623208 0.89 CYP2C9 (0.48) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL11764401 0.89 SMN1; SMN2 (0.44) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL12441784 0.89 MEN1 (0.57) SMN1; SMN2SIGMAR1MEN1KMT2ALMNA
SCHEMBL10598204 0.89 ESR1 (0.57) SMN1; SMN2SIGMAR1MEN1KMT2ACYP3A4
SCHEMBL7809644 0.88 SMN1; SMN2 (0.47) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL11623432 0.87 SMN1; SMN2 (0.43) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL1129210 0.87 SMN1; SMN2 (0.43) SMN1; SMN2SIGMAR1CHRM2CHRM4CHRM5
SCHEMBL11625992 0.87 BCL2 (0.58) SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084956-A Benzo chromene acrylonitrile derivative fluorescent probe and preparation method and application thereof 河南理工大学 2024-05-28 CN claimed
CN-115322345-A High-molecular-weight poly-delta-caprolactone and preparation method and application thereof 南京先进生物材料与过程装备研究院有限公司 2022-11-11 CN claimed
CN-113943317-A Preparation method of MeCBS solid 大连双硼医药化工有限公司 2022-01-18 CN claimed
CN-110497709-A A kind of novel thermosensitive recording materials and preparation method thereof JIANGSU AOLUNDA HIGH TECH IND CO LTD 2019-11-26 CN claimed
CN-108129269-A The method of 1,3- diphenyl -1- propyl alcohol and nitromethane synthesis 1,3- diphenyl -1- propyl alcohol 湖北远大富驰医药化工股份有限公司 2018-06-08 CN claimed
CN-108017518-A 1,3- diphenyl -1- propyl alcohol and preparation method thereof 湖北远大富驰医药化工股份有限公司 2018-05-11 CN claimed
CN-106397083-A Flavonoid drug intermediate 1,1-diphenyl-1-propylene synthesis method 厦门市凯尔利信息科技有限公司 2017-02-15 CN claimed
CN-104356265-A Flame-retardant reinforced polyvinyl chloride-high specific surface area activated carbon carried nanoparticle composite material and preparation method SHAANXI COAL & CHEM TECH INST 2015-02-18 CN claimed
CN-1270996-A Synthesized brake liquid and its production process WUXI CITY OIL REFINERY (CN) 2000-10-25 CN claimed
EP-0459651-B1 Stable acrylic copolymer dispersions SHELL INT RESEARCH (NL) 1996-01-24 EP claimed
EP-0161580-B1 PROCESS FOR THE PREPARATION OF A LACTON F. HOFFMANN-LA ROCHE AG (CH) 1990-11-07 EP claimed
EP-0220906-B1 METAL CARBOXYLATE/ALCOHOL CURING CATALYST FOR POLYCYANATE ESTERS OF POLYHYDRIC PHENOLS INTEREZ, Inc.(a Delaware corporation) (US) 1990-10-31 EP claimed
EP-0116787-B1 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Richter Gedeon Vegyészeti Gyár R.T. (HU) 1987-03-18 EP claimed
EP-0161580-A2 Process for the preparation of a lacton F. HOFFMANN-LA ROCHE AG (CH) 1985-11-21 EP claimed
EP-0034913-B1 STABLE AQUEOUS DISPERSIONS OF MIXED RESINS CELANESE CORPORATION (US) 1984-10-03 EP claimed
EP-0116787-A1 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them Richter Gedeon Vegyészeti Gyár R.T. (HU) 1984-08-29 EP claimed
US-4337334-A HIGH MOLECULAR WEIGHT PHENOLIC BY-PRODUCTS MITSUI TOATSU CHEMICALS INC. (JP) 1982-06-29 US claimed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
US-3994902-A Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds STERLING DRUG INC. (US) 1976-11-30 US disclosed
US-3944590-A ALKYL PHENYL CARBONATES CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA SMN1; SMN2 622/4885SIGMAR1 4436/4885CHRM2 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.