Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13131547 | 0.92 | NPSR1 (0.57) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL936317 | 0.89 | SMN1; SMN2 (0.50) | BCL2KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL246639 | 0.87 | SMN1; SMN2 (0.52) | KMT2AMEN1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28539349 | 0.85 | CHRM2 (0.50) | KMT2AMEN1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL10786071 | 0.84 | ESR1 (0.57) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL7932610 | 0.84 | NPSR1 (0.53) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL11618396 | 0.83 | KIF11 (0.49) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL12157320 | 0.82 | NPSR1 (0.49) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL11757826 | 0.82 | KIF11 (0.50) | BCL2NPSR1KMT2AHTTMEN1 | |
| SCHEMBL11764401 | 0.82 | SMN1; SMN2 (0.44) | BCL2KMT2AMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262139-B | Aminopyrrolotriazines as kinase inhibitors | 百时美施贵宝公司 | 2023-07-25 | — | — | CN | disclosed |
| US-4094908-A | Alpha-substituted benzhydrol derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-06-13 | — | — | US | disclosed |
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |