SCHEMBL936317

SCHEMBL936317

CCC(O)(c1ccccc1)c1ccc(C(O)(CC)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
SIGMAR1 Q99720 1/20 0.48
CHRM2 P08172 3/20 0.46
CHRM4 P08173 3/20 0.46
CHRM5 P08912 3/20 0.46
CHRM1 P11229 3/20 0.46
CHRM3 P20309 3/20 0.46
BCL2 P10415 1/20 0.44
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KCNN4 O15554 1/20 0.43
CYP2D6 P10635 1/20 0.42
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246639 0.97 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL28539349 0.95 CHRM2 (0.50) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL10598204 0.91 ESR1 (0.57) SMN1; SMN2MEN1KMT2ASIGMAR1ESR1
SCHEMBL11764401 0.91 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL11623208 0.91 CYP2C9 (0.48) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL12441784 0.91 MEN1 (0.57) SMN1; SMN2MEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL11623432 0.89 SMN1; SMN2 (0.43) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL1129210 0.89 SMN1; SMN2 (0.43) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL11764142 0.89 KMT2A (0.53) SMN1; SMN2MEN1KMT2ASIGMAR1CHRM2
SCHEMBL11625992 0.89 BCL2 (0.58) SMN1; SMN2MEN1KMT2ABCL2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110008579-A1 MULTI-WALL SHEET WITHOUT THE TRIANGLE EFFECT, COATED BY COEXTRUSION BAYER MATERIALSCIENCE AG (DE) 2011-01-13 US disclosed
US-7824589-B2 Multi-wall sheet without the triangle effect, coated by coextrusion BAYER POLYMERS SHEET EUROPE GMBH (DE) 2010-11-02 US disclosed
US-20040229062-A1 Multi-wall sheet without the triangle effect, coated by coextrusion BAYER POLMERS SHEET EUROPE GMBH (DE) 2004-11-18 US disclosed
US-4929654-A HEAT RESISTANCE, LIGHT RESISTANCE EASTMAN KODAK COMPANY (US) 1990-05-29 US disclosed
EP-0363270-A1 Cyclic phosphites and stabilized polymeric compositions EASTMAN KODAK COMPANY (US) 1990-04-11 EP disclosed