Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926329 | 0.80 | MAPK1 (0.46) | MAPTALDH1A1KDM4EHTTLMNA | |
| SCHEMBL1303826 | 0.76 | CA12 (0.47) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL11620743 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL8656770 | 0.74 | CA12 (0.68) | MAPTALDH1A1HTTCACNA1BAPBA1 | |
| SCHEMBL11468336 | 0.73 | GLA (0.32) | ALDH1A1HTTNPBWR1MAPK1SMN1; SMN2 | |
| SCHEMBL27667923 | 0.71 | CA1 (0.79) | MAPTALDH1A1HTTCACNA1BAPBA1 | |
| SCHEMBL13563469 | 0.70 | STS (0.52) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL9324626 | 0.70 | TSHR (0.72) | MAPTALDH1A1GAAHTTTSHR | |
| SCHEMBL9923544 | 0.70 | CA12 (0.61) | MAPTALDH1A1GAAHTTTSHR | |
| Ethylene Glycol SCHEMBL6701397 | 0.70 | CA12 (0.61) | MAPTALDH1A1HTTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097594-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |