Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621874 | 0.87 | MERTK (0.41) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL10924387 | 0.87 | MEN1 (0.39) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11064204 | 0.83 | NSD2 (0.39) | ALDH1A1L3MBTL1HTTKDM4EHPGD | |
| SCHEMBL11623968 | 0.83 | ALDH1A1 (0.43) | MAPK1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL11621648 | 0.81 | LTA4H (0.44) | SMN1; SMN2LMNA | |
| SCHEMBL11468336 | 0.80 | GLA (0.32) | MAPK1ALDH1A1HTTNPBWR1SMN1; SMN2 | |
| SCHEMBL11620743 | 0.79 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1L3MBTL1POLB | |
| SCHEMBL11473883 | 0.74 | TOP2A (0.48) | KMT2AMEN1ALDH1A1L3MBTL1POLB | |
| SCHEMBL11552165 | 0.74 | LMNA (0.44) | KMT2AALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL8779443 | 0.73 | ALDH1A1 (0.44) | MAPK1KMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497807-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-02-05 | — | — | US | disclosed |
| US-4097594-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |