Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469580 | 0.85 | LTA4H (0.41) | SMN1; SMN2CRHBPCRHR2ALDH1A1RAB9A | |
| SCHEMBL10924387 | 0.83 | MEN1 (0.39) | SMN1; SMN2CRHBPCRHR2ALDH1A1RAB9A | |
| SCHEMBL11621874 | 0.80 | MERTK (0.41) | MAPK1HTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL10926329 | 0.80 | MAPK1 (0.46) | MAPK1HTTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11064204 | 0.80 | NSD2 (0.39) | HTTTDP1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11621648 | 0.77 | LTA4H (0.44) | SMN1; SMN2RAB9A | |
| SCHEMBL10926616 | 0.72 | POLB (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11484840 | 0.72 | F10 (0.39) | SMN1; SMN2 | |
| SCHEMBL5885219 | 0.67 | ST14 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL8779443 | 0.66 | ALDH1A1 (0.44) | MAPK1HTTSMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201780-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |