Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627583 | 0.97 | HRH3 (0.53) | HRH3L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL11625976 | 0.92 | KDM4E (0.44) | HRH3KDM4EMAPTHRH1HRH2 | |
| SCHEMBL11625094 | 0.86 | HRH3 (0.51) | HRH3MEN1KMT2AKDM4EGAA | |
| SCHEMBL11624816 | 0.82 | HRH3 (0.55) | HRH3KDM4EGAAHRH1HRH2 | |
| SCHEMBL11620858 | 0.78 | HRH3 (0.53) | HRH3OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL10503605 | 0.78 | KDM4E (0.48) | HRH3KDM4EGAAHRH1HRH2 | |
| SCHEMBL11627527 | 0.77 | HRH3 (0.45) | HRH3HRH1HRH2OPRK1HTR2A | |
| SCHEMBL11625461 | 0.74 | HRH3 (0.58) | HRH3OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL11626541 | 0.73 | HRH3 (0.53) | HRH3KMT2AOPRK1HTR2ATP53 | |
| SCHEMBL5753115 | 0.72 | LMNA (0.47) | HRH3L3MBTL1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125612-A | N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |