Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.55 |
| ▸ | MC4R | P32245 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625094 | 0.96 | HRH3 (0.51) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11627527 | 0.93 | HRH3 (0.45) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11627583 | 0.86 | HRH3 (0.53) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11623365 | 0.82 | HRH3 (0.49) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11626541 | 0.81 | HRH3 (0.53) | HRH3OPRK1HTR2AALDH1A1HPGD | |
| SCHEMBL10503605 | 0.80 | KDM4E (0.48) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11625461 | 0.80 | HRH3 (0.58) | HRH3OPRK1CYP2D6ALDH1A1OPRM1 | |
| SCHEMBL11625976 | 0.78 | KDM4E (0.44) | HRH3MC4ROPRK1ABCB11CHRM2 | |
| SCHEMBL11623894 | 0.77 | LMNA (0.51) | HRH3OPRK1ABCB11CHRM2ADRA2A | |
| SCHEMBL11623897 | 0.77 | LMNA (0.51) | HRH3OPRK1ABCB11CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125612-A | N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |