Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626067 | 0.85 | SLC6A4 (0.43) | SLC6A4 | |
| SCHEMBL11621089 | 0.84 | SLC6A4 (0.38) | SLC6A4 | |
| SCHEMBL11559263 | 0.80 | ADRA2A (0.34) | SLC6A4CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11621427 | 0.78 | SLC6A4 (0.52) | SLC6A4 | |
| SCHEMBL11619097 | 0.78 | SLC6A4 (0.44) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL11623581 | 0.77 | SLC6A4 (0.51) | SLC6A4 | |
| SCHEMBL11620276 | 0.77 | HTR1A (0.48) | SLC6A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL11620868 | 0.76 | SLC6A4 (0.46) | SLC6A4CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11616798 | 0.76 | HTR1A (0.44) | SLC6A4 | |
| SCHEMBL11617630 | 0.74 | NQO2 (0.43) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073911-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |