Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 3/20 | 0.33 |
| ▸ | HTR1B | P28222 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558795 | 0.83 | HTR1D (0.47) | HTR1AHTR1DHTR1BMPOHTR2A | |
| SCHEMBL11563725 | 0.83 | MPO (0.43) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11624103 | 0.80 | SLC6A4 (0.32) | CYP1A2CYP3A4CYP2C19SLC6A4 | |
| SCHEMBL11479098 | 0.75 | HTR6 (0.49) | HTR1ADRD2DRD4SLC6A4HTR7 | |
| SCHEMBL11556983 | 0.75 | SLC6A4 (0.51) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11463974 | 0.75 | HTR2A (0.65) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11463692 | 0.74 | HTR7 (0.54) | CYP1A2CYP3A4HTR1ASLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL11462601 | 0.74 | HTR1A (0.56) | HTR1ADRD2DRD4SLC6A4DRD3 | |
| Hydrochloric Acid SCHEMBL11462927 | 0.74 | HTR6 (0.49) | HTR1ADRD2DRD4SLC6A4HTR7 | |
| SCHEMBL11554436 | 0.72 | NQO2 (0.45) | SLC6A4HTR1DHTR1BMPOHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147786-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |